Name Potassium Sorbate Description Potassium sorbate is a preservative, the potassium salt of sorbic acid. It is thought that potassium sorbate works as a preservative by inhibits a type of enzyme in the cell called sulphydryl-containing enzymes. It's also thought that the sorbate binds to the cell membrane and either creates a hole in the cell wall or impairs its functioning.
While potassium sorbate does exist in nature, specifically the unripe berries of mountain ash, most potassium sorbate on the market is petroleum-derived. Naturally-derived or synthesized versions are chemically identical with the same toxicological profile. Benefits Inhibits bacterial growth in foods and cosmetics. Considerations • Genotoxic
Potassium sorbate displays genotoxic behavior, with the ability to break DNA in cells. When DNA is damaged, cells can divide improperly and lead to the growth of cancer. Potassium sorbate may also interfere with enzyme activity and gene expression and promote cancer.
• Impairs Gut Function When ingested, potassium sorbate can alter the gut microbiome. One study on zebrafish found that potassium sorbate altered the gut microbiota and hurt the immune system. A mouse study found that potassium sorbate affected the gut microbiome, created liver inflammation, and increased inflammatory markers. • Metabolic Distress
When potassium sorbate enters the body it can create inflammation in the liver. Basically it binds to enzymes in the blood and alters their function, creating a cascade of reactions that end up in an inflammatory response. This can lead to diabetes and metabolic syndrome.
• Skin Absorption There are no clear studies looking at skin absorption of potassium sorbate, however researchers hypothesize a 25% absorption rate. • Skin Irritation
Potassium sorbate may disrupt the skin microbiome, although further studies need to be carried out. Synonyms 24634-61-5
Sorbistat potassium
Sorbistat-K
Potassium (E,E)-sorbate
Sorbic acid potassium salt
590-00-1
potassium (2E,4E)-hexa-2,4-dienoate
Potassium 2,4-hexadienoate
Sorbic acid, potassium salt
BB Powder
Sorbistat-potassium
FEMA No. 2921
Sorbistat k
Potassium sorbate (E)
Caswell No. 701C
Potassium (E,E)-2,4-hexadienoate
Potassium (E,E)-hexa-2,4-dienoate
CCRIS 1894
HSDB 1230
Ins no.202
Potassium (e,e')-sorbate
UNII-1VPU26JZZ4
EINECS 246-376-1
Ins-202
1VPU26JZZ4
2,4-Hexadienoic acid, potassium salt
potassium hexa-2,4-dienoate
Potassium sorbate (e 202)
EPA Pesticide Chemical Code 075902
Potassium 2,4-hexadienoate, (E,E)-
2,4-Hexadienoic acid, potassium salt, (2E,4E)-
CHEBI:77868
AI3-26043
E 202
Potassium sorbate [NF]
2,4-Hexadienoic acid, potassium salt, (E,E)-
Sorbic acid, potassium salt, (E,E)-
potassium;(2E,4E)-hexa-2,4-dienoate
potassium trans,trans-sorbate Research Sources https://www.sciencedirect.com/science/article/pii/S0924224418300050
https://pubmed.ncbi.nlm.nih.gov/20036729/
https://www.ams.usda.gov/sites/default/files/media/CSPotassiumSorbateProposal.pdf
https://pubmed.ncbi.nlm.nih.gov/28229641/
https://pubmed.ncbi.nlm.nih.gov/31596293/
https://pubmed.ncbi.nlm.nih.gov/38211766/
https://pubmed.ncbi.nlm.nih.gov/22570031/
https://pubmed.ncbi.nlm.nih.gov/33656744/
https://dissemination.echa.europa.eu/Biocides/ActiveSubstances/1350-08/1350-08_Assessment_Report.pdf
https://pubmed.ncbi.nlm.nih.gov/36729161/
https://www.ams.usda.gov/sites/default/files/media/P%20Sor%20technical%20advisory%20panel%20report.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477564/
https://pubchem.ncbi.nlm.nih.gov/compound/23676745#section=Depositor-Supplied-Synonyms Summary Avoid in food and cosmetics.