Considerations

• Ethoxylated Chemical Polysorbate 21 is an ethoxylated chemical, meaning it’s been created with ethylene oxide, traces of which, along with its carcinogenic byproduct, 1,4-dioxane, can remain in the product. • May Interfere with Medications Polysorbate 21 may inhibit potential cytochrome P450 enzymes. These enzymes are responsible for breaking down many substances, including drugs, in the body. Inhibiting these enzymes may affect how medications are metabolized in your body, leading to potentially harmful effects. • Disrupts the Gut When ingested, polysorbate 21 can disrupt the gut barrier, leading to inflammation and dysbiosis. Dishwashing soaps that leave polysorbate 21 residue may cause gut barrier damage. • Skin Irritation Polysorbate 21 can be a skin irritant. • Degradation Concerns Polysorbate 21 can be unstable and may require antioxidants or preservatives to keep it stable from oxidation. When polysorbate 21 breaks down it releases hydroperoxides, which break down and create free radicals. • Immune Reaction Polysorbate 21 and other polysorbates can cause severe immune reactions.