Name Dehydroacetic Acid Description Dehydroacetic Acid is an odorless, tasteless white-to-cream crystalline powder used as a plasticizer, bactericide, preservative, and fungicide. Dehydroacetic Acid can be prepared by reacting N-bromosuccinimide with ketene dimer and heating an acetoacetic ester. It is reactive, unstable, and combustible. Because it can be affected by the presence of other chemicals in a formula and degrades over time, it is often used with other preservatives like sodium benzoate or parabens. Benefits NOT found to be a mutagen or reproductive toxin. Considerations • Possible Neurotoxin
Monkeys fed somewhat high doses (3300 mg/kg) of dehydroacetic acid experienced seizures. Hazmap classifies it a neurotoxin. • Acute Toxicity
Large doses can cause vomiting or kidney damage. Do not swallow the raw material. This likely doesn't apply to cosmetic use as it is typically used at 1% or less.
• Contamination Concerns
When exposed to UV light, dehydroacetic acid may form acetaldehyde and formaldehyde. Synonyms DEHYDROACETIC ACID
520-45-6
3-Acetyl-6-methyl-2H-pyran-2,4(3H)-dione
Methylacetopyronone
Biocide 470F
2H-Pyran-2,4(3H)-dione, 3-acetyl-6-methyl-
Acetic acid, dehydro-
3-Acetyl-6-methyl-2,4-pyrandione
3-acetyl-6-methylpyran-2,4-dione
16807-48-0
3-Acetyl-6-methyl-pyran-2,4-dione
DTXSID6020014
3-Acetyl-6-methylpyrandione-2,4
NSC-8770
3-acetyl-6-methyl-3,4-dihydro-2H-pyran-2,4-dione
MFCD00066709
2-Acetyl-5-hydroxy-3-oxo-4-hexenoic acid, .delta.-lactone
Dehydroacetic acid [ISO]
DTXCID9014
SCHEMBL17787
PGRHXDWITVMQBC-UHFFFAOYSA-
NSC8770 Research Sources https://www.cir-safety.org/sites/default/files/Sodium%20Dehydroacetate.pdf
https://pubchem.ncbi.nlm.nih.gov/compound/122903 https://www.tandfonline.com/doi/pdf/10.1080/00021369.1987.10867992 Summary Potential neurotoxin, contamination concerns, acute toxicity.
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