Name Aminomethyl Propanediol Description Aminomethyl propanediol is used as a pH adjuster and fragrance compound in cosmetic formulations. Aminomethyl propanediol can be synthesized by the condensation of the corresponding nitroparaffins with formaldehyde and reduction to the b-aminoalkanols. The reduction to the alkano-lamine is accomplished by hydrogenation in the presence of a Raney nickel catalyst. Benefits Aminomethyl propanediol has NOT been found to be mutagenic or a reproductive toxin. Considerations • Nitrosamine Contamination Aminomethyl propanediol itself does not form nitrosamines, but it may contain impurities that can.
• Skin Irritation At higher concentrations or in susceptible individuals, aminomethyl propanediol may cause skin irritation. Synonyms 2-Amino-2-methyl-1,3-propanediol
115-69-5
2-Amino-2-methylpropane-1,3-diol
AMPD
Aminoglycol
1,3-Propanediol, 2-amino-2-methyl-
Aminomethyl propanediol
Isobutandiol-2-amine
Ammediol
1,1-Di(hydroxymethyl)ethylamine
2-Amino-2-methyl-1,3-propandiol
NSC 6364
MFCD00004678
CZ7BU4QZJZ
2-Amino-2-methylpropan-1,3-diol
2-methyl-2-amino-1,3-propanediol
NSC-6364
1,3-Dihydroxy-2-methyl-2-propylamine
1,3-Dihydroxy-2-amino-2-methylpropane
Amediol
AMPO
UNII-CZ7BU4QZJZ
EINECS 204-100-7
BRN 0635708
AI3-03949
2-amino-2-methyl-propane-1,3-diol
1, 2-amino-2-methyl- Research Sources https://pubmed.ncbi.nlm.nih.gov/19966147/ https://journals.sagepub.com/doi/epdf/10.1177/1091581809350932 https://pubchem.ncbi.nlm.nih.gov/compound/1531 Summary Nitrosamine contamination
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