Name Allantoin Description Allantoin is a compound found in our bodies naturally, as well as the foods we eat. While allantoin may be obtained from natural sources, it is normally prepared synthetically for cosmetic use, either by oxidation of uric acid, reaction of dichloroacetic acid and urea, or condensation reaction between glyoxylic acid and urea. Benefits Allantoin is known for its skin smoothing, skin-softening, and anti-irritant properties. Some studies have found to be helpful in wound healing. • Allantoin has NOT been found to be genotoxic or carcinogenic. • Allantoin has NOT been found to be a common skin irritant or allergen. Considerations • Degradation Concerns
Allantoin starts to degrade once it has been dissolved in water. The purity of the water will affect how much and how fast it will degrade. It is unstable in alkaline conditions so it should not be added to soaps (saponified oils) as the benefits will be deactivated. Typical degradation in water is usually less than 10% after a year. • Inhalation Risk
Allantoin can be harmful if inhaled and should not be used in spray-based products. Smaller particles are more harmful. Synonyms (2,5-dioxoimidazolidin-4-yl)urea Research Sources http://www.thecosmeticchemist.com/molecule_of_the_week/allantoin.html
https://journals.sagepub.com/doi/epdf/10.1177/1091581810362805 Summary May form harmful impurities as it degrades. Lung irritation.
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