Name Polysorbate 20 Description Polysorbate 20 is an emulsifier, surfactant, fragrance ingredient, and skin conditioning agent.
Polysorbate 20 is a polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 (w + x + y + z = 20) and a single terminal is capped by a dodecanoyl group. It has a role as a nonionic surfactant. Benefits Combines water and oil. Considerations • Ethoxylated Chemical
Polysorbate 20 is an ethoxylated chemical, meaning it’s been created with ethylene oxide, traces of which, along with its carcinogenic byproduct, 1,4-dioxane, can remain in the product.
• May Interfere with Medications
Polysorbate 20 may inhibit potential cytochrome P450 enzymes. These enzymes are responsible for breaking down many substances, including drugs, in the body. Inhibiting these enzymes may affect how medications are metabolized in your body, leading to potentially harmful effects. • Disrupts the Gut
When ingested, polysorbate 20 can disrupt the gut barrier, leading to inflammation and dysbiosis. Dishwashing soaps that leave polysorbate 20 residue may cause gut barrier damage. • Skin Irritation
Polysorbate 20 can be a skin irritant. • Degradation Concerns
Polysorbate 20 can be unstable and may require antioxidants or preservatives to keep it stable from oxidation. When polysorbate 20 breaks down it releases hydroperoxides, which break down and create free radicals. • Immune Reaction
Polysorbate 20 and other polysorbates can cause severe immune reactions. Synonyms Polyoxyethylene (20) sorbitan monolaurate
7T1F30V5YH
Polyethylene glycol (44) sorbitan monolaurate
Polyethylene glycol (80) sorbitan monolaurate
Polyethylene glycol 4000 sorbitan monolaurate
Polyethylene glycol 500 sorbitan monolaurate
Polyoxyethylene (10) sorbitan monolaurate
Polyoxyethylene (44) sorbitan monolaurate
Polyoxyethylene (75) sorbitan monolaurate
Polyoxyethylene (80) sorbitan monolaurate
Polyoxyethylene 20 sorbitan monolaurate
FEMA No. 2915
POE 20 Sorbitan monolaurate
PSML
Polyethylene glycol 2000 Sorbitan Laurate
Polyoxyethylene (4) sorbitan monolaurate
Sorbimacrogol laurate 300
Sorbitan monolaurate, ethoxylated
20s, Polysorbate
Armotan pml-20
CCRIS 699 Research Sources https://pubchem.ncbi.nlm.nih.gov/compound/Polysorbate%2020 https://pubmed.ncbi.nlm.nih.gov/19041719/
https://pubmed.ncbi.nlm.nih.gov/37530764/
https://pubmed.ncbi.nlm.nih.gov/36464527/
https://pubmed.ncbi.nlm.nih.gov/30758866/ https://pubmed.ncbi.nlm.nih.gov/32171713/
https://pubmed.ncbi.nlm.nih.gov/17973307/
https://www.sciencedirect.com/topics/chemistry/hydroperoxide#:~:text=Hydroperoxides%20are%20unstable%20intermediates%20of,either%20nonradical%20or%20radical%20mechanisms. https://pubmed.ncbi.nlm.nih.gov/16400901/ Summary Ethoxylated chemical can be contaminated with carcinogenic ethylene oxide and/or 1,4-dioxane.