Name Cocamidopropylamine oxide Description Cocamidopropylamine Oxide is created by reacting coconut oil with dimethylaminodpropylamine and then further reacted with hydrogen peroxide to form cocamidopropylamine oxide. Benefits Cocamidopropylamine Oxide is a tertiary amine oxide. It acts as a surfactant, foam booster, and hair conditioning agent in cosmetic items. Considerations • Contamination Concerns
According to CTFA (1997), Cocamidopropylamine Oxide contains ≤3000 ppm free amidoamine and ≤5 ppm free DMAPA. Commercial products made with amine oxides may contain “unreacted amine and various other products originating from different stages of synthesis” Amidoamines are a class of chemicals with the potential to be skin allergens or irritants. DMAPA, aka Dimethylaminopropylamine, is also a known skin irritant. Workers involved in the production of cocamidopropylamine oxide may be exposed to Dimethylaminopropylamine and experience lung damage from inhalation. It is also corrosive to skin and eyes and an irritant at even low concentrations. Synonyms Amides, coco, N-(3-(dimethylamino)propyl), N-oxide
N-(3-(Dimethylamino)propyl) coco amides N-oxides
Amides, coco, N-(3-(dimethylamino)propyl), N-oxides
Cocamidopropyldimethylamine oxide
3-Cocoamidopropyl dimethylamine oxide
N-(Cocoamidopropyl)-N,N-dimethylamine, oxide
Cocoamido-3-propyldimethylamine oxide
3-(N,N-Dimethylamino)propyl cocoamido amine oxide
Coco amides, N-(3-(dimethylamino)propyl), N-oxide
N-(3-(Dimethylamino)propyl)coco amides-N-oxide
N,N-Dimethyl-N-(3-cocamidopropyl)amine oxide
N,N-Dimethyl-N-(3-(coconut oil alkyl)amidopropyl)amine oxide
EINECS 268-938-5 Research Sources https://www.atamanchemicals.com/cocamidopropylamine-oxide_u25186/#:~:text=Cocamidopropylamine%20Oxide%20(CAO)%2C%20Cocamidopropyl,peroxide%20to%20form%20Cocamidopropylamine%20Oxide.
https://journals.sagepub.com/doi/pdf/10.1080/10915810802032396 https://pubchem.ncbi.nlm.nih.gov/compound/3-Dimethylaminopropylamine https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/chem_background/exsumpdf/dimethylaminopropylamine_508.pdf https://pubchem.ncbi.nlm.nih.gov/substance/135320409 Summary Cocamidopropylamine Oxide is a synthetic chemical with partial natural feedstocks. On its own, it's a fairly harmless ingredient, however it can be contaminated with harmful irritants.