Considerations

• Quaternary Ammonium Compound Cetrimonium bromide is considered a quaternary ammonium compound, a class of chemicals linked to mitochondrial damage and endocrine disruption. There is limited reproductive toxicity data available for this ingredient. It has not been tested for endocrine disruption in humans. EWG Skin Deep Database states Associated with endocrine disruption and One or more animal studies show reproductive effects at moderate doses but does not cite their data sources. • Eye Irritation Caused irreversible eye damage at a 25% concentration in lab tests. Common usage rates are considerably lower (typically .001% – 4%), although it may cause eye irritation in some circumstances. • Developmental Toxin Caused embryo effects when fed at high doses to lab rats. • Organ Damage Prolonged or repeated exposure to high amounts may result in organ damage. • Respiratory Irritation Aerosolized products containing cetrimonium bromide may induce respiratory irritation. • Toxic to Aquatic Life Considered an environmental toxin with long-lasting effects. • Intestinal Effects Animal studies have found cetrimonium bromide to exhibit some disruption and mitochondrial damage in the gut.